Subclass and avidity of circumsporozoite protein specific antibodies associate with protection status against malaria infection
Abstract RTS,S/AS01 is an advanced pre-erythrocytic malaria vaccine candidate with demonstrated vaccine efficacy up to 86.7% in controlled human malaria infection (CHMI) studies; however, reproducible immune correlates Configuration Board of protection (CoP) are elusive.To identify candidates of humoral correlates of vaccine mediated protection, we